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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MKNK2
All Species:
34.55
Human Site:
S243
Identified Species:
69.09
UniProt:
Q9HBH9
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HBH9
NP_060042.2
465
51875
S243
N
G
D
C
S
P
I
S
T
P
E
L
L
T
P
Chimpanzee
Pan troglodytes
XP_512248
805
84821
S570
N
G
D
C
S
P
I
S
T
P
E
L
L
T
P
Rhesus Macaque
Macaca mulatta
XP_001117579
489
54064
S267
N
G
D
C
S
P
I
S
T
P
E
L
L
T
P
Dog
Lupus familis
XP_855041
1044
109683
S835
N
G
D
C
S
P
I
S
T
P
E
L
L
T
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8CDB0
459
51614
S243
N
G
D
C
S
P
I
S
T
P
E
L
L
T
P
Rat
Rattus norvegicus
Q5U2N4
459
51555
S243
N
G
D
C
S
P
I
S
T
P
E
L
L
T
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001235171
508
56331
T291
N
S
A
C
T
P
I
T
T
P
E
L
T
T
P
Frog
Xenopus laevis
Q6P431
467
52653
S242
N
S
D
C
S
P
I
S
T
P
E
L
L
T
P
Zebra Danio
Brachydanio rerio
NP_997888
472
52923
S243
N
S
D
S
S
P
I
S
T
P
E
L
L
T
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_731624
1090
123424
A226
T
D
I
S
S
P
A
A
T
P
Q
L
L
T
P
Honey Bee
Apis mellifera
XP_395927
516
58135
A216
N
S
L
S
S
P
V
A
T
P
Q
L
L
T
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_779905
511
56921
P277
Y
N
T
P
V
T
T
P
E
L
L
T
P
V
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
42.8
92.4
34.6
N.A.
92.6
92.6
N.A.
N.A.
60.8
76.8
73.3
N.A.
24
49.8
N.A.
48.7
Protein Similarity:
100
48.5
93.4
36.8
N.A.
95.2
95.2
N.A.
N.A.
73
87.7
84.5
N.A.
31
66.6
N.A.
64.5
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
66.6
93.3
86.6
N.A.
53.3
60
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
80
93.3
86.6
N.A.
66.6
80
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
0
0
9
17
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
67
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
67
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
9
0
75
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
50
0
0
0
0
0
0
0
0
0
0
0
0
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
9
0
0
0
75
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
9
0
0
0
0
0
0
9
9
92
84
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
84
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
9
0
92
0
9
0
92
0
0
9
0
92
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
17
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
34
0
25
84
0
0
67
0
0
0
0
0
0
0
% S
% Thr:
9
0
9
0
9
9
9
9
92
0
0
9
9
92
0
% T
% Val:
0
0
0
0
9
0
9
0
0
0
0
0
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _